Charles Edward Wetzel (August 25, 1894 - March 7, 1941) was a pitcher in Major League Baseball who played briefly for the Philadelphia Athletics during the 1927 season. Listed at 6' 1", 162 lb., Wetzel batted and threw right-handed. He was born in Jay, Oklahoma.
Little is known about this player on an Athletics uniform. Wetzel was 32 years old when he entered the majors on July 27, 1927, and did not have a decision or strikeouts. Wetzel posted a 7.71 ERA in two games, including one start, giving up four earned runs on eight hits and five walks in 4 ⅔ innings of work. As a hitter, he went 1-for-2 with a run scored. He pitched his final game on July 28, and never appeared in a major league game again.
Following his majors career, Wetzel pitched and managed in the Minor leagues.
Wetzel died in Globe, Arizona, at the age of 46.